CHEMICAL VERSUS PHYSICAL SURFACE MODIFICATION OF TITANIUM DENTAL IMPLANTS: A COMPARATIVE REVIEW OF SANDBLASTED, LARGE-GRIT, ACID-ETCHED (SLA) AND FEMTOSECOND LASER-ABLATED SURFACES
DOI:
https://doi.org/10.67772/yhs75v15Keywords:
Dental implants, Osseointegration, Surface topography, Sandblasted acid-etched, Femtosecond laser, TitaniumAbstract
Surface topography governs the rate and quality of osseointegration of titanium dental implants. The sandblasted, large-grit, acid-etched (SLA) surface represents the established chemical-subtractive paradigm and remains the clinical benchmark21[SP1.1], whereas femtosecond (fs) laser ablation has emerged as a physical-subtractive alternative that promises deterministic topographic control, superior surface purity and a thickened, crystalline oxide without the mechanical penalties of acid etching. This review critically compar es the two paradigms across four domains: surface metrology and chemistry, In-vitro biological response, In-vivo biomechanical fixation and histomorphometry, and clinical implications. Evidence indicates that SLA reliably produces a moderately rough (Sa 1–2 µm) surface with high bone-to-implant contact and more than 95% five-year survival, but is constrained by residual alumina embedding, hydrogen-induced embrittlement and stochastic topography. Femtosecond laser processing generates hierarchical micro/nano structures (laser-induced periodic surface structures, LIPSS) with a five-fold thicker oxide, controllable anatase/rutile content, contaminant-free chemistry and markedly enhanced osteoblast adhesion, at the cost of frequently hydrophobic wettability, limited long-term in vivo data and a modest fatigue reduction. The strongest bone-bonding biomechanical data derived from laser-structured (predominantly nanosecond) surfaces, while fs-specific evidence remains largely in vitro and material-scientific. It is concluded that fs-laser ablation is a credible, and in several respects superior, engineering platform whose osteogenic and antibacterial promise is not yet matched by clinical validation. Rational, scenario-based selection guidelines and future directions toward “smart” dual-function surfaces are proposed.
References
1. Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52(2):155-70.
2. Le Guéhennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium dental implants for rapid osseointegration. Dent Mater. 2007;23(7):844-54.
3. Buser D, Schenk RK, Steinemann S, Fiorellini JP, Fox CH, Stich H. Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs. J Biomed Mater Res. 1991;25(7):889-902.
4. Cochran DL, Schenk RK, Lussi A, Higginbottom FL, Buser D. Bone response to unloaded and loaded titanium implants with a sandblasted and acid-etched surface: a histometric study in the canine mandible. J Biomed Mater Res. 1998;40(1):1-11.
5. Buser D, Broggini N, Wieland M, Schenk RK, Denzer AJ, Cochran DL, et al. Enhanced bone apposition to a chemically modified SLA titanium surface. J Dent Res. 2004;83(7):529-33.
6. Orsini G, Assenza B, Scarano A, Piattelli M, Piattelli A. Surface analysis of machined versus sandblasted and acid-etched titanium implants. Int J Oral Maxillofac Implants. 2000;15(6):779-84.
7. Schupbach P, Glauser R, Bauer S. Al₂O₃ particles on titanium dental implant systems following sandblasting and acid-etching. Materials. 2019;12(11):1735.
8. Yokoyama K, Ichikawa T, Murakami H, Miyamoto Y, Asaoka K. Fracture mechanisms of retrieved titanium screw thread in dental implants. Biomaterials. 2002;23(12):2459-65.
9. Madaan VU, Mapara M, Padhye AM. Comparative evaluation of microroughness created on titanium alloy subjected to two different acid etching techniques: an in vitro study. J Contemp Dent. 2016;6(1):1-8.
10. Makary C, Menhall A, Zammare C, Lombardi T, Lee SY, Stacchi C, et al. Bone-to-implant contact of machined, SLA and nanostructured calcium-incorporated surfaces in human posterior maxilla: a randomized split-mouth study. Nanomaterials. 2023;13(2):357.
11. Rodriguez-Gonzalez R, Monsalve-Guil L, Jimenez-Guerra A, Velasco-Ortega E, Moreno-Munoz J, Nunez-Marquez E, et al. Relevant aspects of titanium topography for osteoblastic adhesion and inhibition of bacterial colonization. Materials. 2023;16(9):3553.
12. Palmquist A, Lindberg F, Emanuelsson L, Brånemark R, Engqvist H, Thomsen P. Biomechanical, histological, and ultrastructural analyses of laser micro- and nano-structured titanium alloy implants: a study in rabbit. J Biomed Mater Res A. 2010;92(4):1476-86.
13. Shah FA, Johansson ML, Omar O, Simonsson H, Palmquist A, Thomsen P. Laser-modified surface enhances osseointegration and biomechanical anchorage of commercially pure titanium implants for bone-anchored hearing systems. PLoS One. 2016;11(6):e0157504.
14. Lackington WA, Schweizer P, Khokhlova M, Cancellieri C, Guimond S, Chopard-Lallier AL, et al. Femtosecond laser-texturing the surface of Ti-based implants to improve their osseointegration capacity. Adv Mater Interfaces. 2022;9(31):2201164.
15. Beltran AM, Giner M, Rodriguez A, Trueba P, Rodriguez-Albelo LM, Vazquez-Gamez MA, et al. Influence of femtosecond laser modification on biomechanical and biofunctional behavior of porous titanium substrates. Materials. 2022;15(9):2969.
16. Kolobov YR, Zhidkov MV, Golosov EV, Vershinina TN, Kudryashov SI, Ionin AA, et al. The formation of oxide layers on a titanium surface by irradiation with femtosecond laser pulses. Tech Phys Lett. 2018;44(12):1092-5.
17. Schweitzer L, Schoon J, Cunha A, Pereira T, Mika K, do Rego AMB, et al. Preclinical in vitro assessment of submicron-scale laser surface texturing on Ti6Al4V. Materials. 2020;13(23):5342.
18. Hadzik J, Kubasiewicz-Ross P, Simka W, Gebarowski T, Barg E, et al. Fractal dimension and texture analysis in the assessment of experimental laser-induced periodic surface structures (LIPSS) dental implant surfaces – in vitro study. Materials. 2022;15(8):2713.
19. Tavangar A, Tan B, Venkatakrishnan K. Synthesis of three-dimensional TiO₂ nanofibrous structures by femtosecond laser processing for bioactivation of titanium. [Date unknown – verify against source PDF].
20. Wennerberg A, Albrektsson T. Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res. 2009;20(Suppl 4):172-84.
21. Buser D, Janner SF, Wittneben JG, Brägger U, Ramseier CA, Salvi GE. 10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients. Clin Implant Dent Relat Res. 2012;14(6):839-51.
22. Rupp F, Scheideler L, Olshanska N, de Wild M, Wieland M, Geis-Gerstorfer J. Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces. J Biomed Mater Res A. 2006;76(2):323-34.
23. Albrektsson T, Wennerberg A. On osseointegration in relation to implant surfaces. Clin Implant Dent Relat Res. 2019;21 Suppl 1:4-7.
24. Vorobyev AY, Guo C. Direct femtosecond laser surface nano/microstructuring and its applications. Laser Photon Rev. 2013;7(3):385-407.
25. Jemat A, Ghazali MJ, Razali M, Otsuka Y. Surface modifications and their effects on titanium dental implants. Biomed Res Int. 2015;2015:791725.
26. Faeda RS, Tavares HS, Sartori R, Guastaldi AC, Marcantonio E Jr. Evaluation of titanium implants with surface modification by laser beam: biomechanical study in rabbit tibias. Braz Oral Res. 2009;23(2):137-43.
27. Gittens RA, Olivares-Navarrete R, Schwartz Z, Boyan BD. Implant osseointegration and the role of microroughness and nanostructures: lessons for spine implants. Acta Biomater. 2014;10(8):3363-71.
28. Att W, Hori N, Takeuchi M, Ouyang J, Yang Y, Anpo M, et al. Time-dependent degradation of titanium osteoconductivity: an implication of biological aging of implant materials. Biomaterials. 2009;30(29):5352-63.
29. Mombelli A, Hashim D, Cionca N. What is the impact of titanium particles and biocorrosion on implant survival and complications? A critical review. Clin Oral Implants Res. 2018;29 Suppl 18:37-53.
30. Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;14(3):251-62.
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