EPH - International Journal of Medical and Health Science

COLORECTAL CANCER SCREENING “LITERATURE REVIEW”

Tue, 13 Feb 2024 00:00:00 +0000

According to the World Health Organization (WHO), screening consists of presumptively identifying, using tests applied
in a systematic and standardized manner, subjects suffering from a previously past disease or abnormality. unnoticed.
Screening tests must make it possible to divide people who are apparently healthy but who are probably suffering from a
given disease or abnormality from those who are probably free from it, Four controlled population studies were carried
out in Europe to test the feasibility and effectiveness of mass screening for colorectal cancer: Nottingham (Great Britain),
Funen (Denmark), Burgundy (France) and Gothenburg (Sweden). . The first three studies included subjects aged 45 or
50 to 74 years old. The Hemoccult test was offered every 2 years to half of the target population, the other half served as
a control. The Swedish study, involving subjects aged 60 to 64, is of limited interest because the screening test was only
carried out twice with simple follow-up afterwards

CRITERIA FOR ULTRASOUND SUSPICION OF THYROID NODULE

Radia. Benyahia, Ali. Gaoua, Kamel. Hail, Chahira Mazouzi, Nabil Raa, SE. Bendib — Tue, 13 Feb 2024 00:00:00 +0000

A thyroid nodule is a formation well differentiated from the rest of the thyroid. It represents the most frequent thyroid
pathology, and the majority of these nodules are benign. Assessment of patients with thyroid nodules includes history,
clinical examination, TSH measurement and thyroid ultrasound.
In this article, we will detail the criteria for suspicion, including the place of ultrasound in the evaluation of thyroid
nodules, based on the EU-TIRADS criteria

STUDY OF GRM 6 METABOTROPIC GLUTAMATE RECEPTOR 6 GENE IN NIGHT BLIND FAMILIES

Sat, 17 Feb 2024 00:00:00 +0000

Night blindness is characterized by poor vision in low light and is frequently related to retinal rod cell degeneration.
While it can be congenital and classified as an Autosomal recessive ambiguity, it is regarded as rare around the world
and is usually distincted from X chromosome. The study focused on families that had the history of night blindness, and
entire blood samples were taken for DNA extraction. Exon 4 of the GRM6 gene was targeted using specific primers to
amplify the targeted DNA fragments. Gel electrophoresis and sequencing techniques were used to examine the
amplified fragments. However, there were no significant alterations in the GRM6 Exon 4 area in our findings,
indicating that this specific gene may have no role in night blindness in the examined families. The work emphasizes the
significance of comprehending the numerous genetic mechanisms that contribute to congenital fixed night blindness, as
well as the involvement of the GRM6 gene in retinal function. The study focused at the GRM6 gene in connection to
congenital stationary night blindness (CSNB). The GRM6 gene was premeditated in seven families having night
blindness symptoms. Blood samples were taken, DNA was extracted by organic method and specific primers for Exon 4
of the GRM6 gene were designed. Gel electrophoresis was performed that indicated the successful PCR amplification
and subse

RARE ASSOCIATION BETWEEN CLUBBING AND ESOPHAGEAL SQUAMOUS CELL CARCINOMA

Wegdan H Babekir, Abdelmounem E Abdo — Wed, 21 Feb 2024 00:00:00 +0000

We present a case of loweroesophagealsquamous cell carcinoma accompanied by bilateral finger and toe clubbing,without evidence of distant spread. This case serves to demonstrate that this presentation, although rarely mentioned inthe literature, can occur. Digital clubbing is a well-documented finding in various cardiac and pulmonary conditions, butis less commonly observed in liver and inflammatory bowel diseases.Patients usually present towards the end of the
disease progression when they have esophageal cancer.